Symposium Speaker

Dr. Chee Wai Chua

Shanghai Jiao Tong University, China

Dr. Chee Wai Chua is a Principal Investigator at Clinical Research Stem Cell Center, State Key Laboratory of Oncogenes and Related Genes,and an Adjunct Professor at Department of Urology, Shanghai Jiao Tong University School of Medicine affiliated Renji Hospital. He has been appointed as a Professor of Special Appointment, which carries the title “Eastern Scholar” by Shanghai Institutions of Higher Learning, and also selected for the Shanghai Jiao Tong University School of Medicine “Double Hundred” Talent Program. Dr. Chua received a Bachelor of Biomedical Science with Honors from National University of Malaysia in 2002, and was awarded a Ph.D. in Cancer Biology upon the completion of his graduate work at Department of Anatomy, Li Ka Shing Faculty of Medicine, The University of Hong Kong in 2009. Hethen joined Professor Michael Shen’s group at Columbia University Medical Center (CUMC) for post doctoral training and was later promoted to an Associate Research Scientist position at Departments of Urology and Medicine,CUMC in 2014. At Columbia, Dr. Chua had pursued studies of genetically engineered mouse models of prostate cancer and prostate stem cell biology. In particular, he received the Department of Defense Prostate Cancer Research ProgramPostdoctoral Training Award to functionally analyze the role of androgen receptor in a prostate luminal progenitor population.More importantly, Dr. Chua has developed a novel organoid culture method for maintaining prostate luminal progenitors, prostate and bladder cancers as well as metastases. In the first ever organoid workshop held at Cold Spring Harbor Laboratory, he served as a Laboratory Instructor to teach the prostate organoid culture methodology. Currently, Dr. Chua’s groupfocuseson the investigation of intrinsic and extrinsic regulation of androgen receptor independence in the prostate using genetically engineered mouse models, tissue recombination assay and the newly established organoid technology.

Talk title:
Functional analysis of androgen receptor-independent prostate epithelial progenitors